Phosphatidylserine

Key Benefits

Memory, Focus, Learning, Problem-Solving, Language Skills, Locomotor Functions

Summary

Phosphatidylserine is a phospholipid found in the membranes of cells, particularly in the brain. It plays a crucial role in maintaining cellular function, especially in nerve cells, which are vital for cognitive processes. Historically, Phosphatidylserine has been appreciated for its role in supporting brain health and cognitive function, with natural sources including foods like soybeans, white beans, egg yolks, and certain types of fish such as mackerel and herring.

Why We Use It in Our Nootropic Stack

Phosphatidylserine is a key ingredient in our nootropic stack due to its profound impact on various aspects of cognitive function. It is known to improve the formation of short-term memory and the consolidation of long-term memory, ensuring that new memories are effectively stored and can be retrieved when needed. This phospholipid also enhances the brain's ability to create new memories, learn and recall information, and focus attention and concentrate on tasks.

Research into Phosphatidylserine underscores its importance in maintaining cognitive sharpness and supporting overall brain health. Studies show that it enhances memory, learning, and problem-solving abilities, while also aiding in the quick and efficient execution of motor functions.

Scientific Studies of Phosphatidylserine on Brain Health and Memory

  1. Study 1: Glade, M. J., & Smith, K. (2015). "Phosphatidylserine and the human brain."
    • Summary: This review discussed the impact of phosphatidylserine on cognitive health. It found that phosphatidylserine supplementation could support human cognitive functions by improving the formation of short-term memory, the consolidation of long-term memory, the ability to create new memories, the ability to retrieve memories, the ability to learn and recall information, the ability to focus attention and concentrate, the ability to reason and solve problems, language skills, and the ability to communicate. It also supports locomotor functions, especially rapid reactions and reflexes.
    • Reference: https://pubmed.ncbi.nlm.nih.gov/25933483/ 
    • Citation: Glade MJ, Smith K. Phosphatidylserine and the human brain. Nutrition. 2015 Jun;31(6):781-6. doi: 10.1016/j.nut.2014.10.014. Epub 2014 Nov 4. PMID: 25933483.
  2. Study 2: Crook, T. H., Tinklenberg, J., Yesavage, J., Petrie, W., Nunzi, M. G., & Massari, D. C. (1991). "Effects of phosphatidylserine in age-associated memory impairment."
    • Summary: This study evaluated the effects of phosphatidylserine on age-related memory impairment. Results indicated that supplementation could improve memory and cognitive function in older adults.
    • Reference: https://pubmed.ncbi.nlm.nih.gov/2027477/ 
    • Citation: Crook TH, Tinklenberg J, Yesavage J, Petrie W, Nunzi MG, Massari DC. Effects of phosphatidylserine in age-associated memory impairment. Neurology. 1991 May;41(5):644-9. doi: 10.1212/wnl.41.5.644. PMID: 2027477.
  3. Study 3: Jorissen, B. L., Brouns, F., Van Boxtel, M. P. J., & Riedel, W. J. (2002). "Safety of phosphatidylserine administration in elderly people."
    • Summary: The study assessed the safety of phosphatidylserine supplementation in the elderly. It concluded that phosphatidylserine is well-tolerated and could offer cognitive benefits for older individuals.
    • Reference: https://pubmed.ncbi.nlm.nih.gov/12385596/ 
Citation: Jorissen BL, Brouns F, Van Boxtel MP, Riedel WJ. Safety of soy-derived phosphatidylserine in elderly people. Nutr Neurosci. 2002 Oct;5(5):337-43. doi: 10.1080/1028415021000033802. PMID: 12385596.

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